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Walker Payne, a divorced ex-con and deadbeat dad, doesn't have much going for him. About all he's got is his loyal best friend, a pit bull named Brute.

Eight adventurers brave the perilous jungles of Borneo in pursuit of the fountain of youth, unawarethey're being stalked by gigantic snakes that feed on human flesh.

When two matriarchs and long-time friends become mired in their families' bickering, gossip and crazy business, they decide to escape on a cross-country road trip where they rediscover themselves and find a way to save their families from ruin.